Author

Zhongsong Zhang

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Review Open access Sep 2026

Precision Multimodal Nanodynamic Therapy for Lung Cancer: From Tumor Microenvironment-Responsive Platforms to Cell-Death Reprogramming and Immune Remodeling

Abstract Lung cancer remains one of the most prevalent and lethal malignancies worldwide and is characterized by a complex tumor microenvironment (TME), including severe hypoxia, acidosis, elevated glutathione levels, and pronounced immunosuppression. These pathological conditions compromise the efficacy of conventiona...

Keyi Gou, Zhong-Song Zhang, Si-Xian Yi et al. · International Journal of Nan... · 0 citations

Review Open access Sep 2026

Nanomedicine-Empowered CAR-T Therapy for Multiple Myeloma: Toward Programmable, Durable, and Precision Immunotherapy

Abstract Multiple myeloma (MM) remains a difficult-to-cure hematologic malignancy. Although B-cell maturation antigen (BCMA)-targeted chimeric antigen receptor T-cell (CAR-T) therapy has substantially deepened clinical responses in patients with relapsed/refractory MM, its broader clinical application remains constrain...

Can Huang, Xu-Yan Zhang, Yuanyin Teng et al. · International Journal of Nan... · 0 citations

Review Open access Aug 2026

Engineering Multimodal Nanomaterials for Prostate Cancer Theranostics: Design Principles, Recent Advances, and Translational Challenges

Abstract Prostate cancer (PCa) remains a major clinical challenge because of limitations in early detection, tumor heterogeneity, therapeutic resistance, and metastatic progression. Nanomaterials provide versatile platforms for PCa theranostics by integrating molecular imaging, biomarker detection, targeted delivery, m...

Jia Wang, Zhongsong Zhang, Haihao Li et al. · International Journal of Nan... · 0 citations