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Author

Zhou-Ke Tan

2 papers indexed here

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Open access Oct 2026

Biodegradable ROS-Responsive TPCD Nanoparticles Mitigate Cisplatin-Induced Acute Kidney Injury via Synergistic Antioxidant and Immunomodulatory Actions

Background Acute kidney injury (AKI) is a serious condition with high incidence and mortality rates, yet effective clinical treatment options remain limited. The therapeutic efficacy of small-molecule antioxidants such as N-acetylcysteine (NAC) is limited by their difficulty in targeting the kidneys and their rapid cle...

Qin Wang, Wen Zhen, Zhou-Ke Tan et al. · 0 citations
Open access Aug 2026

Tubular ACSM3 controls fatty acid metabolism and safeguards against acute kidney injury in male mice

Kidney tubular epithelial cells exceptionally exhibit high energy demands and preferentially metabolize long-chain fatty acids via fatty acid oxidation (FAO), where the impairment of FAO represents a hallmark of acute kidney injury (AKI). However, the role of medium-chain fatty acid metabolism in kidney injury remains...

Feng-Ping Zhang, Li Feng, Ting Xiang et al. · 0 citations

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