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Zhou Zhong

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Review Open access Oct 2026

Immunomodulation and biofilm disruption of piezoelectric materials in bone infection

Bone infection remains a persistent clinical challenge due to biofilm formation, antibiotic resistance, and impaired bone regeneration. This manuscript focuses on the application of piezoelectric biomaterials in the treatment of bone infection and systematically elucidates their ability to convert in vivo mechanical st...

Zhen Wang, Kai-Xue Zheng, Yun-Feng Tang et al. · 0 citations
Review Open access Oct 2026

Bioactive small-molecule gas delivery for enhanced bone regeneration: modulation of cellular signaling and remodeling of the regenerative microenvironment

This mini-review summarizes the biological roles and biomaterial-based delivery strategies of nitric oxide, carbon monoxide, hydrogen sulfide, hydrogen sulfide, oxygen, and hydrogen in bone repair and demonstrates promising outcomes in critical-sized, osteoporotic, diabetic, inflammatory, and aging-related bone defects...

Zhou Zhong, Biao Cao, Xin Duan · 0 citations

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