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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Zhou Zhou

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Open access Jul 2026

Human single-cell atlas of proliferative diabetic retinopathy reveals a SOX15-overexpressing stromal population driving retinal fibrosis through the endothelin-1 -EDNRB axis

Key pathological features of the human PDR retina are identified, including pervasive neuroinflammation and selective loss of photoreceptor subpopulations, and the SOX15–EDN1-EDNRB axis is delineated as a novel mechanism driving retinal fibrosis.

Fen Tang, Wenjing He, Zhi-Jie Niu et al. · 0 citations

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