Author

Zhu-Jun Liu

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Open access Sep 2026

Ganoderic Acid A Ameliorates Pentylenetetrazol‐Induced Epilepsy in Mice via Activating KCNQ2

ABSTRACT Trial Design This study aimed to explore the antiepileptic effect of Ganoderic acid A (GA‐A) on pentylenetetrazol (PTZ)‐induced epilepsy in mice and clarify its underlying mechanism, focusing on the KCNQ2 channel. Methods C57BL/6 mice and hippocampal‐specific KCNQ2 knockout mice were used to establish PTZ‐indu...

Yang Yao, Zhu-Jun Liu, Xu-Jiao Wang et al. · CNS Neuroscience & Therapeut... · 0 citations

Review Open access

Advances in the pharmacological research of Ganoderma lucidum: from traditional Chinese medicine to modern clinical applications

This review systematically summarizes extraction, structural characteristics and quality control bottlenecks of ganoderma lucidum, and elaborates comprehensive preclinical pharmacological effects covering immunoregulation, neuroprotection, cardiovascular and renal protection, gastrointestinal homeostasis, anti-tumor, a...

Yu-Kun Zhang, Yang Yao, Zhu-Jun Liu et al. · Traditional Medicine Researc... · 0 citations

Aug 2026

Toxicity-guided assessment of disinfection by-products via machine learning and network toxicology.

A toxicity-guided and interpretable framework integrating molecular modeling, machine learning, network toxicology, and experimental characterization is developed to systematically predict and prioritize potentially high-risk disinfection by-products, supporting evidence-based water quality management.

Jie Wang, Zhu-Jun Liu, Ruipeng Lai et al. · Water Research · 0 citations