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Zhuo-Er Li

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Review Open access Sep 2026

Organelle-centered ISG15 biology: distinguishing covalent ISGylation from interferon-associated responses

ISGylation is an interferon-inducible ubiquitin-like post-translational modification mediated by the interferon-stimulated gene 15 conjugation system. Initially characterized as an antiviral effector pathway, ISGylation is now increasingly recognized as a regulator of organelle homeostasis and cellular stress responses...

Zhuo-Er Li, Chunli Wang, Jin-Rong Zhang et al. · 0 citations

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