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Author

Zhuo-Yi Cai

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Review Open access Sep 2026

The Dual Role of Exosome-Mediated Central-Peripheral Immune Dialogue in Amyotrophic Lateral Sclerosis-Associated Neuroinflammation

Objective Amyotrophic lateral sclerosis (ALS) is increasingly viewed as a multisystem disorder in which central–peripheral immune communication may modify neuroinflammation. Exosomes, an endosome-derived subset of extracellular vesicles (EVs), have been proposed as mediators of this communication, but the strength and...

Tao Jin, Bing-Jie Yang, Zhuo-Yi Cai et al. · 0 citations
Review Open access Aug 2026

Mechanisms and Clinical Assessment of Fear of Disease Progression in Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a progressive, life-limiting neurodegenerative disease characterized primarily by motor dysfunction, although cognitive and behavioral impairment occurs in a substantial subset of patients. Progressive functional decline and prognostic uncertainty may contribute to pronounced fear...

Ting Wang, Tao Jin, Zhuo-Yi Cai et al. · 0 citations

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