Open access
Sep 2026
Chemo-metallo nanodrivers for spatiotemporally controlled in situ vaccination
In situ cancer vaccines exhibit promising therapeutic potential; however, their efficacy is constrained by limited antigen release, suboptimal spatiotemporal immune coordination, and adaptive immune resistance. In this study, we identify zinc ions (Zn2+) as synergistic agents with chemotherapeutics in modulating PANopt...
Xian-Min Li, Hua-Li Lei, You-Dong Chen et al.
· Science Advances · 0 citations