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Open access Oct 2026

Rank Normalization Enables Cross Pathway Comparison in Degradation Resolved Proteome Turnover Analysis

Protein homeostasis, or proteostasis, is essential for cellular health, and its disruption contributes to cancer, aging, and neurodegenerative disease. Proteostasis is maintained largely by two intracellular degradation systems: the ubiquitin proteasome system (UPS) and the autophagy lysosomal pathway (ALP). Here, we c...

Zi Gao, Qiang Xiao, Jeffery W. Kelly et al. · 0 citations

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