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Author

Zi-Han Wang

2 papers indexed here

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Open access Aug 2026

Glycolytic enolase 1-induced H4K12 lactylation activates quiescent breast cancer stem-like cells in triple-negative breast cancer

Activation of quiescent or extremely slow-cycling breast cancer stem-like cells (qsBCSCs) contributes to tumor progression, yet the regulatory mechanisms involved in triple-negative breast cancer (TNBC) remain elusive. We developed a dual-reporter system combining NANOG-EGFP and H2B-mCherry pulse-chase labeling to sepa...

Shuai Liu, Yunfeng Ma, Yuanyuan Zeng et al. · 1 citation
Open access Sep 2026

Physics-informed self-supervised denoising for fluorescence microscopy via structure and intensity priors

Summary Fluorescence microscopy images contain smooth, low-intensity backgrounds dominated by random noise and brighter biological signals with complex textures. We incorporate these structural and intensity characteristics into self-supervised denoising through two complementary modules. Structure-adaptive probabilist...

Mu-Bo Zhang, Zi-Han Wang, Jun-Qiu Chen et al. · 0 citations

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