Zi-Han Ye

Multi-Omics Analysis Identifies Fibroblast-Associated Stromal–Immune Networks Linked to Pregnancy-Associated Attenuation of Imiquimod-Induced Psoriatic Dermatitis

Background: Psoriasis is a chronic, immune-mediated inflammatory skin disorder that frequently exhibits spontaneous clinical remission during pregnancy. However, the underlying cell-type-specific transcriptomic alterations—particularly the involvement of dermal fibroblasts and hormone receptor signaling—remain poorly u...