Author

Zi-Jun Wang

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Sep 2026

KEAP1 loss-of-function suppresses immunogenic ferroptosis and limits PD-1 blockade efficacy through an NRF2-FSP1 pathway.

Loss-of-function mutations in Kelch-like ECH-associated protein 1 (KEAP1) frequently occur in lung adenocarcinoma and are associated with poor prognosis and limited benefit from immunotherapy. However, the mechanisms linking KEAP1 deficiency to immune evasion remain elusive. We combined clinical data analysis, in vivo...

Yu-Xin Yao, Xin-Feng Wang, En-Zhi Yin et al. · Cancer Letters · 0 citations

Preprint Aug 2026

Sharp Root Anti-Concentration via Projective Incidence and Ordered Root Laws

This paper answers the one-dimensional local root anti-concentration questions posed by Balcan, Pegden, and Sharma in the context of online optimization of piecewise-Lipschitz functions. For a homogeneous feature curve and coefficients whose density relative to the uniform law on a symmetric convex body $K$ is bounded...

Zi-Jun Wang, Yuchen Miao, Yifan Hu et al. · 0 citations