Author

Zi-Mo Zhou

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Review Aug 2026

Advances in the study of the role of bone immunity in physiological and pathological processes related to bone metabolism.

The net skeletal effect of the immune system is determined by the balance of interacting cell types, cytokine networks, and signaling pathways, and systematic evaluation of combination strategies pairing immunomodulators with anti-resorptive, anabolic agents, or senolytics.

Zhuoru Jin, Lisheng Liu, He-Ran Wang et al. · International Immunopharmaco... · 0 citations

Review Jul 2026

Aging of Mesenchymal Stem Cells in Bone Aging: Mechanisms, Impact, and Therapeutic Perspectives.

Aging of the skeleton is a hallmark of organismal decline and underlies prevalent age-related disorders such as osteoporosis and osteoarthritis. Bone marrow-derived mesenchymal stem cells (BMSCs), the primary source of osteoblasts, undergo profound functional deterioration during senescence, leading to an imbalance bet...

Zimo Zhou, Heran Wang, Zhuoru Jin et al. · Ageing Research Reviews · 1 citation