Author

Zi-Rui Wang

2 papers indexed here

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Open access Sep 2026

Gefitinib-based therapy in refractory hepatocellular carcinoma with EGFR overexpression: a spatial profiling-guided case report

Current systemic treatments for advanced hepatocellular carcinoma (HCC) such as antiangiogenic targeted therapies, immune checkpoint inhibitors (ICIs), and their combinations have shown benefit, but widespread drug resistance severely limits patient outcomes and underscores an urgent need for effective post-progression...

Qin Xu, Xiao-Fen Li, Rui Zhu et al. · Frontiers in Immunology · 0 citations

Aug 2026

Establishing a genetic mutation panel for predicting malignant transformation of oral leukoplakia: A prospective cohort study.

OBJECTIVE To investigate somatic mutations in the whole genes of tissue samples from patients with oral leukoplakia (OLK), as the most typical precursor of oral cancer; and identify the specific genes as a mutational panel for predicting OLK malignant transformation. METHODS A total of 123 consecutive OLK patients wi...

Yuhan Zhu, Zi-Rui Wang, Chen-Xi Li et al. · Oral Oncology · 0 citations