Open access
Aug 2026
Paeoniflorin Alleviates Oxygen–Glucose Deprivation/Reoxygenation Injury by Mediating Crosstalk Between Neurons and Endothelial Cells Through the VEGF/PI3K-AKT/mTOR Pathway
Paeoniflorin alleviated CIRI by directly protecting neurons and indirectly modulating neuron–endothelial crosstalk through VEGF/PI3K-AKT/mTOR activation, supporting its multi-target therapeutic potential.
Zi-Shuo Xu, Hong Luo, Yi-Ming Zhao et al.
· Pharmaceuticals · 0 citations