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Open access Sep 2026

FAP53 facilitates formation of microtubule doublets.

The formation of microtubule doublets (MTDs) is a foundational step in cilia biogenesis, yet how B-tubule nucleation is initiated at the molecular level remains elusive. Here, we identify FAP53 as a factor that facilitates B-tubule assembly in a scaffold-dependent manner. In vitro reconstitution demonstrated that recom...

Ming Li, Guang-Han Chen, Zhe Chen et al. · 0 citations

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