Zi-Xi Zhou

S1P1-mediated metabolic reprogramming promotes astrocytic mitochondrial dysfunction via histone lactylation in subarachnoid hemorrhage

Mitochondrial dysfunction is a central event in the pathophysiology of subarachnoid hemorrhage (SAH). Accumulating evidence has demonstrated that mitochondrial function is vulnerable to metabolic alterations. While the role of neuronal mitochondrial dysfunction in SAH pathology is firmly established, less is know...