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Zi-Yan Yang

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Open access Sep 2026

Sphallerocarpus gracilis Polyphenols Alleviate DSS-Induced Colitis by Remodeling Gut Microbiota and Inhibiting the AGE-RAGE/HMGB1 Pathway

As a traditional Tibetan medicine and health food, the fleshy roots of Sphallerocarpus gracilis were adopted to extract polyphenol powder(PP) in this research. Using a DSS-induced colitis mouse model combined with multi-omics analysis and experimental validation, we explored the protective effects and molecular mechani...

Xuan-Jun Wang, Jun Zhang, Sai-Zhen Guo et al. · 0 citations
Aug 2026

Dendrobine activates the SIRT3-SOD2 axis to protect keratinocytes from UVB-induced oxidative damage.

DDB protects keratinocytes from UVB-induced oxidative damage and apoptosis by directly activating the SIRT3-SOD2 axis, thereby restoring mitochondrial redox homeostasis and establishing DDB as a promising natural candidate for functional foods or pharmaceuticals aimed at preventing skin photoaging and preserving mitoch...

Jing Xu, Ti-Ti Liu, Zi-Yan Yang et al. · 0 citations

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