Author

Ziyang Gao

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Open access Oct 2026

Structural network alterations and peripheral immune-inflammatory dysregulation define distinct subtypes of major depressive disorder with prognostic implications

Abstract Background Immune-inflammatory dysregulation and cortical structural vulnerability have been increasingly implicated in major depressive disorder (MDD). However, how they interact with each other, and whether immune heterogeneity in MDD is systematically organized by structural networks, remain unclear. Method...

W. Du, M. Yuan, Zi-Yang Gao et al. · Psychological Medicine · 0 citations

Oct 2026

The network localization and underlying biological basis of heterogeneous structural and functional brain abnormalities in insomnia disorder.

Insomnia disorder (ID) has become a prevalent sleep disorder worldwide, yet its underlying neural mechanisms remain unclear due to heterogeneous neuroimaging findings and uncertain network localization. We identified brain structural and functional abnormality locations associated with ID from 63 published neuroimaging...

Wei-Jie Xue, Zi-Yang Gao, Yuan Shi et al. · Sleep · 0 citations

Jul 2026

Cortical wiring cost abnormalities in mesial temporal lobe epilepsy with hippocampal sclerosis: implications for postoperative seizure recurrence.

Abnormalities of cortical wiring costs were observed in mTLE-HS, particularly in patients with postoperative seizure recurrence, offering novel insights into the underlying pathophysiology of this illness and providing potential for outcome prediction.

Fei Zhu, Bo Tao, Yue Li et al. · Journal of Neurosurgery · 0 citations