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Zi-Yang Wu

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Oct 2026

A fine-tuning-guided virtual screening workflow identifies cell-active small-molecule hits targeting Gq-mediated signaling.

A prioritization workflow that combines target-specific fine-tuning of a pretrained drug-target interaction model, pharmacophore filtering, and structure-based docking to identify candidate Gq-modulating compounds from commercial libraries is developed.

Zi-Yang Wu, Xin Chen, Hang Su et al. · 0 citations

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