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Zi-Yang Zhou

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Open access Sep 2026

Early adjunctive vasopressin was not associated with a lower 7-day risk of renal replacement therapy in norepinephrine-treated patients with cirrhosis: a target-trial-informed study with external replication

Background Early adjunctive vasopressin can reduce catecholamine exposure in vasodilatory shock, but whether it prevents severe kidney failure in norepinephrine-treated patients with cirrhosis is uncertain. Methods We conducted a target-trial-informed landmark study using MIMIC-IV as the primary cohort and eICU-CRD as...

Wei Zhang, Ke-Yan Miao, Hui Chen et al. · 0 citations

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