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Zi-Yi Chen

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Open access Sep 2026

DNA methylation signatures distinguish gout from asymptomatic hyperuricaemia and converge with genetic risk at immune-metabolic loci.

OBJECTIVES Why only a minority of hyperuricaemic individuals develop gout remains unclear, and epigenetic differences between these states are poorly characterised. We aimed to define DNA methylation signatures distinguishing gout from asymptomatic hyperuricaemia and evaluate their utility for molecular stratification....

Zi-Yi Chen, Hao-Fan Ren, Xiao-Peng Ji et al. · 0 citations

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