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Author

Zi-Yue Yin

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Review Aug 2026

Beyond Monotherapy: The Evolving Role of CTLA-4 in Combination Immunotherapy for Gastrointestinal Cancers.

CTLA-4 blockade with Ipilimumab or Tremelimumab shows promise, especially combined with PD-1/PD-L1 inhibitors, yielding enhanced antitumor immunity in microsatellite instability-high/deficient mismatch repair (MSI-H/dMMR) tumors with high immune infiltration.

Fuyuan Ma, Jingyuan Ma, Yaofan Lu et al. · 0 citations

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