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Aug 2026

Zebrafish USP14 Suppresses RIG-I-Mediated Innate Antiviral Immunity via Targeted Deubiquitination to Facilitate SVCV Replication.

Innate immunity serves as the host's primary defense against viral infection. Aberrant immune activation can trigger tissue damage and autoinflammatory disorders, which requires precise negative regulation to sustain immune homeostasis. RIG-I is a vital pattern recognition receptor that governs antiviral innate immune...

Hongying Zhang, Jihuan Hu, Chuxin Wu et al. · 0 citations
Aug 2026

Development of an oral Lactobacillus casei-based recombinant vaccine expressing GCRV-II multi-epitope fusion protein and its protective efficacy against grass carp hemorrhagic disease.

Results demonstrate that the recombinant L. casei vaccine LC-VP4274-367-367-VP5105-336-NS38143-338 is a promising oral vaccine candidate for protecting grass carp against GCRV-II infection.

Xi-jian Chen, Yujiao Chen, Dan-Wen Wang et al. · 0 citations

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