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Zijian Chen

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Open access Oct 2026

Low‐Density Lipoprotein Receptor‐Targeted Biomimetic Nanoplatform Suppresses Glioblastoma Stemness and Remodels Antitumor Immunity via Dual Metabolic Disruption

ABSTRACT Glioblastoma (GBM) remains one of the most lethal malignancies because durable tumor control is constrained by limited brain‐tumor drug exposure, metabolic plasticity, stem‐like tumor states, and an immunosuppressive microenvironment. We developed apolipoprotein B fragment‐decorated nanoparticles co‐loaded wit...

Yi-Ning Jiang, Wen-Zhuo Yang, Wen-Ting Cheng et al. · 0 citations
Open access Oct 2026

Diversity and Predicted Functional Profiles of Wheat Seed Endophytic Microbiota Associated with Grain Nutritional Quality Traits

Wheat seed endophytic microbiota may be associated with seed nutritional quality, yet systematic studies on this relationship remain limited. In this study, nine representative wheat cultivars were selected from more than 600 wheat accessions based on starch and protein contents and classified into three groups: high-s...

Han-Rui Shi, Kang-Jie Yu, Rui Luo et al. · 0 citations
Open access Aug 2026

Brain imaging-derived phenotypes influence risk of bipolar disorder: comprehensive exposome-wide association and wide-angled genetic analyses

An atlas of brain IDPs associated with bipolar disorder is established, by integrating epidemiological and genetic evidence, and candidate IDPs that were consistently associated with BD are highlighted across complementary analyses.

Wen-Zhuo Yang, Lin Pan, Hao-Qun Xie et al. · 0 citations

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