Author

Zijian Li

2 papers indexed here

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Open access Sep 2026

Plasma untargeted metabolomics reveals metabolic signatures associated with epilepsy and anti-seizure medication responsiveness.

Background Epilepsy is a neurological disorder with heterogeneous anti-seizure medication responses and a lack of peripheral biomarkers for diagnosis and drug resistance assessment. This study aims to explore metabolic alterations and candidate metabolite panels associated with epilepsy and anti-seizure medication resp...

Zi-Jian Li, Zhen Liang, Juan Ren et al. · Frontiers in Molecular Biosc... · 0 citations

Open access Aug 2026

Amino acid- and lipid-related metabolic remodeling in PTZ-kindled mice reveals candidate plasma signatures of chronic epilepsy

PTZ-induced kindling was associated with marked plasma metabolic alterations involving amino acid-, tryptophan-, and lipid-related pathways, which supports the broader relevance of metabolic dysregulation to epilepsy, while the mechanistic roles and biomarker potential of individual metabolites require independent vali...

Juan Ren, Fu-Li Wang, Zi-Jian Li et al. · Frontiers in Neuroscience · 0 citations