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Zirong Jiang

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Open access Aug 2026

TRIB3 promotes triple-negative breast cancer metastasis by restricting lipophagy through the PI3K/AKT/mTOR signaling pathway.

A previously unrecognized mechanism by which TRIB3 regulates lipophagy to drive TNBC metastasis is uncovered, highlighting TRIB3 as a central mediator of TNBC progression and suggesting novel therapeutic strategies targeting lipophagy for this aggressive breast cancer subtype.

L. Ruan, Jian-Feng Liu, Zirong Jiang · 0 citations

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