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Zitong Zhao

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Aug 2026

Living Microbe-Driven Bioorthogonal Catalysts Enables Cytotoxin Generation, Cuproptosis and Lactate Depletion for Synergistic Tumor Therapy.

A living bacterial hybrid reactor is developed by integrating Shewanella oneidensis MR-1 with Cu(II)-based zeolitic imidazolate frameworks to enable metabolism-guided and tumor-confined bioorthogonal catalysis, overcoming key limitations of conventional bioorthogonal catalysis and enabling precise, tumor-confined thera...

Li-Li Xia, Xiangxuan Chao, Zitong Zhao et al. · 0 citations

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