Open access
Aug 2026
Senescence-related immunosuppressive gene MFAP2 orchestrates stromal-immune crosstalk and immunotherapy resistance in gastric cancer
MFAP2 is a hub SRIG linking eCAFs, ECM remodeling, and immune escape in GC, which serves as a reliable prognostic and ICI resistance predictor and potential therapeutic target, providing a basis for precision therapy in GC.
Yi-Chan Hu, Liao-Xiang Zhu, Lijun Zhou et al.
· BMC Cancer · 0 citations