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Author

Zoltán K. Nagy

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2 papers indexed here

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Aug 2026

Integrating Bayesian Optimization for Enhancing Parameter Estimation Workflows for Modeling Crystallization Processes

Accurate estimation of kinetic parameters is essential for developing population balance models in crystallization processes. Parameter estimation (PE) problems are often formulated as black-box optimization tasks, which are computationally expensive due to the large parameter space and the wide variability of crysta...

Yash Barhate, Zoltán K. Nagy · 0 citations
Open access Aug 2026

Enhanced Scale-Up of Rotor-Stator Wet Milling Using Population Balance Modeling with a Novel Exponential Shear-Activated Kernel

Wet milling is a critical operation in drug substance manufacturing, enabling control of the particle size distribution of active pharmaceutical ingredients. Scaling up of the wet milling process usually involves equipment change. Due to material availability limitations during the early stage of development, there i...

Kensaku Matsunami, Álmos Orosz, Varun Sundarkumar et al. · 1 citation

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