Review
Open access
Aug 2026
Integrated histopathology and single-cell transcriptomics reveal distinct pathological features and foamy macrophage characteristics in spinal tuberculosis and brucellar spondylitis
Histopathological comparison showed that STB and BS were both dominated by chronic inflammation but exhibited distinct lesion patterns, and Macro4 is best interpreted as a BS-associated lipid-remodelled macrophage state supported by convergent histological and transcriptomic evidence.
Qiang Liu, Han-Hua Guo, Jun-Xiao Liu et al.
· Frontiers in Immunology · 0 citations