Review
Open access
Jul 2026
Ubiquitin-driven regulation of immune checkpoints in lung cancer: Mechanisms and therapeutic implications (Review)
A synthesis concerning how a dynamic balance between E3 ubiquitin ligases (E3s) and deubiquitinases (DUBs) dictates the fate of key checkpoint proteins, including programmed cell death protein 1/programmed death-ligand 1, lymphocyte-activating gene 3 and B7 homolog 4 is offered.
Lin Chai, Lin-Rong Pang, Yi-Ting Li et al.
· Experimental and Therapeutic... · 0 citations