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Open access Sep 2026

NMN Mitigates LPS-Induced Liver Injury by Inhibiting Ferroptosis via Suppression of the cGAS-STING-ACSL4 Axis.

Sepsis often leads to severe liver damage, and currently few effective therapies are available for it. Nicotinamide mononucleotide (NMN), a well-known anti-aging agent, exerts organ-protective effects, yet its detailed mechanisms against acute liver injury remain poorly understood. Here, we established LPS-induced live...

Yan Liao, Cheng-Long Zhu, Wangzheqi Zhang et al. · 0 citations
Review Sep 2026

Reshaping the ncRNA Regulatory Network: Decoding the Pathological Mechanisms and Novel Therapeutic Paradigms of Heart Failure.

Heart failure (HF) is a significant global health issue, and its complicated pathogenesis needs to be further clarified. In recent years, non-coding RNAs (ncRNAs) have emerged as key players in the development and pathogenesis of HF; nonetheless, their systemic regulatory networks and clinical translational capacity ne...

Yu-Jie Wang, Xuan Yin, Hao-Ling Zhang et al. · 0 citations
Review Open access Sep 2026

Protein Post-Translational Modifications in the Regulation of Ferroptosis: New Opportunities and Challenges for Cancer Immunotherapy

Ferroptosis is an emerging form of programmed cell death driven by the excessive accumulation of iron-dependent lipid peroxides, which plays a pivotal regulatory role in suppressing tumor initiation and progression. In recent years, protein post-translational modification (PTM), as a core molecular mechanism regulating...

Xin Xie, Li-Zhou Song, Zhao-Yu Li et al. · 0 citations

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