Author

Zuo-Tao Zhao

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Review Open access Oct 2026

Bruton Tyrosine Kinase Inhibitors in Immune-Mediated Skin Diseases: Current Evidence and Future Directions

Bruton tyrosine kinase (BTK) is a central signaling molecule that links the B-cell receptor (BCR), Fc receptors, and Toll-like receptors (TLRs). By coordinating signaling in B cells, mast cells, macrophages, and other immune cells, BTK occupies an important position in cutaneous immune responses. BTK inhibitors (BTKis)...

Zi-Han Wang, Jun-Chen He, Ting Zhang et al. · International Journal of Mol... · 0 citations

Case report Open access Sep 2026

Facial discoid lupus erythematosus complicated by a Candida tropicalis fungal granuloma in a patient with rhupus syndrome: a case report of successful treatment with oral itraconazole

Discoid lupus erythematosus (DLE) is a chronic cutaneous subtype of lupus erythematosus characterized by inflammatory lesions that are highly susceptible to secondary infection, particularly in immunocompromised individuals. Cutaneous fungal granulomas caused by Candida tropicalis and superimposed on pre-existing DLE l...

Ling-Ling Dong, Ting Zhang, Tong Hua et al. · Frontiers in Medicine · 0 citations