Dawn Sivan, K. S. Kumar, T. M. Kumar et al.
· Next Materials · 0 citations
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Rim Zrelli, H. Misson, M. Attia et al.
· Journal of Systems and Softw... · 1 citation
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Oussama Zabraoui, Yahya Hmamou, Anas Chafi et al.
· Computers & Industrial E... · 0 citations
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Z. Zeman, A. Mikkola, Grzegorz Orzechowski et al.
· Advanced Engineering Informa... · 1 citation
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Mingqiao Mo, Hao Zhang, Yu-an Tan et al.
· Knowledge-Based Systems · 2 citations
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Panpan Qiu, Jianzhuo Yan, Hongxia Xu et al.
· Advanced Engineering Informa... · 0 citations
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Feiran Wang, Yonghao Du, Lining Xing et al.
· Engineering applications of... · 0 citations
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Shiyuan Yin, Ruizhi Zhang
· Knowledge-Based Systems · 0 citations
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The Membership Decoding method is a plug-and-play replacement for standard decoding that requires only black-box token probabilities, and a new token-level membership inference method is proposed by leveraging likelihood from reference models, shifting the generation from the original token distribution to the member token distribution.
Zitai Chen, Reza Shokri
· Proceedings on Privacy Enhan... · 0 citations
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Tianlin Liu, Cheng Yang, Hyungchul Chung et al.
· Transportation Research Part... · 0 citations
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Haichao Du, Dongwei Zheng, An Guo et al.
· Engineering applications of... · 0 citations
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Accurate classification of long non-coding RNAs (lncRNAs) is essential for transcriptome annotation and understanding gene regulation. Existing computational methods predominantly rely on nucleotide sequence features, frequently overlooking biologically relevant peptide signals encoded within lncRNAs. To overcome this limitation, we developed LncPNdeep, an integrative deep learning framework that combines nucleotide and peptide embeddings extracted via masked language models, specifically utilizing contextual representations from BigBird, Longformer, and ProtTrans. By fusing both features in a concatenated neural architecture, LncPNdeep robustly captures complex sequence relationships and improves discrimination between lncRNAs and coding RNAs. Benchmarking on the human transcriptome achieved state-of-the-art performance with 97.1% accuracy, surpassing established lncRNA classification tools and baseline machine learning models. LncPNdeep also demonstrated superior generalization ability across cross-species datasets, maintaining consistently high accuracy and F1 scores. Permutation analysis highlighted the pivotal role of peptide embeddings, especially Average Peptide Embedding, in model performance, while t-SNE visualizations confirmed that integrating multiple embeddings markedly enhances the separation of lncRNAs from coding RNAs. These results position LncPNdeep as a versatile and powerful tool for transcriptomic research, facilitating lncRNA discovery, biomarker identification, and comparative genomics. The model and instructions are freely available at https://github.com/yatoka233/LncPNdeep.
Zongrui Dai, Feiyang Deng, Hsiao H. Sung
· Non-coding RNA Research · 0 citations
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