Cell mimicry arises when different cell types appear morphologically similar. Human pathologists resolve this ambiguity using surrounding tissue context, whereas current vision models either lack contextual reasoning (cell foundation models) or cannot operate at the cell level (pathology MLLMs). We present Loki-OT, which propagates region-level tissue reasoning to individual cell predictions via Unbalanced Optimal Transport, using MLLM-derived density priors as soft guidance for ambiguous cell reassignment. Loki-OT is motivated by the observation that pretrained cell foundation model features already encode discriminative information, including tissue context, but standard cell-level supervision fails to use tissue context effectively. The resulting transport plan is distilled into a lightweight student MLP classifier that learns context-aware decision boundaries within the pretrained feature space. On the independent TCGA-BRCA cohort, Loki-OT achieved lower patient-level MAE than the fully supervised in-domain PanopTILs classifier and improved F1 in epithelium-rich mimicry tissues, using 278 weak region-level MLLM estimates built on a general-domain cell foundation model. Code: https://github.com/xiangli980/Lymphocyte_Mimicry_Correction_via_Loki_OT
Xiang Li, Yuqi Wang, Casey C. Heirman et al.· 0 citations
A comparative study of four audits applicable to pre-trained, black-box face generators, which consistently reveal substantial identity distinguishability while reporting markedly different epsilon estimates that reflect each method's distinct assumptions and finite-sample treatment.
Arman Zareian Jahromi, Vishnu Bondalakunta, M. Shah et al.· 0 citations
A DT-based IDS that jointly models physical relationships among decoded powertrain signals and identifies attacks through residuals between predicted and observed behavior shows promise for detecting stealthy payload-level CAN attacks that preserve normal communication patterns, supporting behavior-based cybersecurity for connected and automated vehicles.
Araf Rahman, M. Salek, Mashrur Chowdhury· 0 citations
Entanglement-Weighted Pruning (EWP), an unlearning procedure for quantum federated learning that scores every trainable circuit parameter with the product of two signals: the diagonal entry of the quantum Fisher information matrix estimated on the target client's data via the parameter-shift rule, and a structural entanglement weight associated with the parameter's gate.
Aditya Kumar, S. Chongder· 0 citations
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This work investigates the potential of the waste hierarchy from the EU's Waste Framework Directive, which suggests five different measures for how to manage waste: prevention, reuse, recycling, recovery, and disposal, and calls to attention that prevention of unnecessary use of LLMs carry huge potential for lowering the climate impact of the models.
E. Husom, M. Nylund, Ophelia Prillard· 0 citations
The massive overactuation in the human musculoskeletal system makes it challenging to train musculoskeletal models to generate human-like motion via reinforcement learning, primarily because exploration in the resulting high-dimensional and redundant action space is extremely inefficient. To address this problem, we propose the $\lambda$-hold controller, inspired by the equilibrium-point (EP) hypothesis, which has been widely supported by extensive evidence from human motor control studies. The policy's control variable is the per-muscle EP threshold length $\lambda$, from which a stretch-reflex recruitment law computes the muscle excitations automatically. Holding each $\lambda$ over an interval of the gait phase also sharply reduces the frequency at which the policy must be queried. Consequently, the controller, to our knowledge for the first time, enables a muscle-actuated skeletal model to learn human-like sprinting using only a minimal reward within an hour of training. The efficient exploration through the proposed $\lambda$-hold controller is not merely an engineering trick but an approach grounded in physiology, bringing together the EP hypothesis, intermittent control, and optimal feedback control. Beyond encapsulating human-like behavior in predictive simulation, this achievement contributes to developing a learnable model of the human motor controller.
Jun Hyuk Lee, Chihyeong Lee, Jooeun Ahn· 0 citations
VLCP closes the loop where the failure actually lives, on the control code, within a single episode, and keeps the VLM frozen, which is a training-free policy with a tenfold gap between pooled success and confidence intervals in every scene family.
Dhia Naouali, Ming Wu, Claudia Wong et al.· 0 citations
This work proposes a margin-regularized structured semantic alignment framework that directly aligns brain embeddings with text embeddings in a shared semantic space, enabling retrieval-based decoding and enables explicit modeling of the correspondence between neural representations and language semantics.
FedPref lets institutions with unequal, unpooled data benefit from collaboration without ever sharing reports or annotations, and frozen public language models propose alternative JSON extractions, local annotations rank them, and sites collaboratively train compact Qwen3-8B adapters while sharing only model updates.
Flint Xiaofeng Fan, Cheston Tan, Y. Ong et al.· 0 citations
LLM-based code generation is now embedded in mission-critical pipelines, but defenses against vulnerable output remain post-hoc -- static analyzers, fine-tuned classifiers, or an LLM judge that screen completed code, ignoring the generating model's own internal state. We test a narrower, directly measurable question: when an LLM reads a piece of C/C++ code as context, do its hidden activations already carry a signal about that code's vulnerability status? We extract last prefill token activations from four LLMs (Granite-4.1-8B, Qwen3.5-9B, Qwen3.6-27B, Gemma-4-12B) across three model families and train MLP probes on these activations. We evaluate them on four function-level C/C++ benchmarks (Devign, Big-Vul, Draper VDISC, PrimeVul). Our probes achieve 41.7\% average F1 using 13.4--16.0M-parameter probes -- under 0.2\% of base-model size. On Devign, the best probe (Qwen3.5-9B, 68.8\% F1) matches the published fine-tuned-classifier SOTA (67.9\%) despite reading only a frozen, general-purpose LLM's activations; on the harder, more imbalanced benchmarks (Big-Vul, Draper VDISC, PrimeVul) probes trail SOTA substantially. This is early evidence that a coding LLM's own representation of arbitrary code is informative about that code's vulnerability status, motivating further work toward lightweight, model-native vulnerability screening.
A novel characteristic of dataset heterogeneity is introduced by employing the norm of the difference between the maximum and minimum points in the classical terms of functional analysis.
Maksim V.Kukushkin, M. Arbatskiy, D. Balandin et al.· 0 citations
MagViT, an interpretable multi-magnification transformer framework with scale-gated fusion and patient-level model selection, is presented, an interpretable multi-magnification transformer framework with scale-gated fusion and patient-level model selection relative to prior ViT-centered BreakHis work.
Nabil Ashab, Soumitra Kundu, Saif Mahmud Parvez et al.· 0 citations
A new machine-learning framework aims to improve the success rate of computational protein design while moving away from results that reproduce sequences found in nature.
MIT News · Artificial Intelligence· news.mit.eduAug 24, 2026
A new method for surgically removing training examples from a model reveals that as datasets grow, the link between what a model learns and what it produces dissolves.
