Diffusion-Conditioned Representation Alignment (DCRA), a training framework that repurposes the forward diffusion process as a structured corruption scheduler for representation learning, and produces more balanced and structured representations compared to baseline and diffusion-only models.
Abstract
Learning robust representations for time-series signals under noise and distribution shifts remains challenging, especially in clinical applications such as electroencephalogram (EEG) and electrocardiogram (ECG) analysis. We propose Diffusion-Conditioned Representation Alignment (DCRA), a training framework that repurposes the forward diffusion process as a structured corruption scheduler for representation learning. Different from conventional augmentation and consistency-based methods that rely on independently sampled perturbations, DCRA introduces a structured corruption trajectory via the diffusion forward process, which enables continuous and controlled representation evolution across noise levels. We introduce a feature-level consistency objective that aligns representations across noise levels while preserving class-discriminative structure. This mechanism promotes structure-preserving consistency, which enables smooth and semantically coherent feature trajectories in latent space. The proposed framework is encoder-agnostic and can be integrated with state space models and Transformer architectures. The seizure detection experiments on the CHB-MIT EEG dataset show that DCRA consistently improves performance under multiple noise conditions and achieves higher sensitivity at low false-positive rates. Analysis reveals that DCRA produces more balanced and structured representations compared to baseline and diffusion-only models. These findings highlight the benefit of combining structured corruption with representation alignment for robust time-series learning.
Electroencephalography (EEG) is a critical tool for monitoring brain activity and diagnosing neurological disorders such as epilepsy. However, learning meaningful representations from raw EEG signals remains challenging due to limited annotations, substantial inter-subject variability, and complex temporal dynamics. Re...
Hong-Pu-Ah Jia, Sim Kuan Goh, Zi-Wei Zhang et al.· IEEE journal of biomedical a...· 7 citations
Sample-level reliability heterogeneity is common in deep time series learning. Standard training pipelines apply a uniform regularization setting to all samples, which can under-regularize corrupted samples and over-restrict clean samples. Common robustness approaches filter observations in data space or impose priors...
Si-Ru Zhong, Sen-Zhang Wang, James T. Kwok et al.· arXiv.org· 0 citations
Introduction Deep learning has revolutionized image analysis, yet most clinical biosignals, especially multi-lead electrocardiograms (ECGs), remain one-dimensional and awkward for modern vision models. Methods We introduce an orthogonal-polynomial imaging (OPI) framework that encodes 12-lead ECGs into a single two-dime...
Karan Singh, Pingal Pratyush Nath, U. Sinha et al.· Frontiers in Artificial Inte...· 0 citations
Across modalities, the results show that explicitly encoding measurable cyclic structure improves physiological time-series restoration and proposes antithetic coupling of reverse trajectories to reduce sampling variance while achieving comparable performance with fivefold fewer network evaluations.
Samuel Ruipérez-Campillo, Michele Copetti, Jorge da Silva Goncalves et al.· arXiv.org· 1 citation
A Mamba-augmented model is proposed that inserts selective state-space blocks at the convolutional bottleneck, combining local feature extraction with long-range temporal modeling at linear complexity, and substantially improves ST/T-change diagnoses, which depend on broad, context-sensitive waveforms.
B. Morel, Samuel Ruipérez-Campillo, Andreas P. Streich et al.· arXiv.org· 0 citations
A hybrid CNN-SSM-Attention backbone for 12-lead ECG classification is introduced, which provides strong supervised baselines under a compact parameter budget and improves transfer, particularly in reduced-label settings and under both full fine-tuning and LoRA-based adaptation.
Y. Bazi, Sarah Aljuhani, M. M. Al Rahhal et al.· arXiv.org· 0 citations
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