HSOA Journal of Psychiatry, Depression & Anxiety

Treatment-Resistant Depression: A Literature Review of Innovative and Emerging Treatment Strategies

Introduction and objective: Major depressive disorder (MDD) is a heterogeneous psychiatric condition characterized by affective, cognitive and somatic symptoms that considerably impair daily functioning. It is defined clinically by prolonged low mood, diminished interest or pleasure, and a range of associated disturban...

Understanding Stress and its Management in Unani Medicine: A Psychoneuroimmunological and Pharmacological Review

Stress-related disorders, including generalized anxiety disorder, clinical depression, and psychosomatic illnesses, constitute a substantial and growing component of the global burden of disease and account for approximately 12–15% of mental health consultations worldwide.¹ Although modern medicine commonly employs tar...

Prevalence of Anxiety, Depressive Symptoms, and Substance Use in Schizophrenia.

Background: Schizophrenia is a chronic and debilitating psychiatric disorder often accompanied by comorbid conditions, notably anxiety, depressive symptoms, and substance use disorders. These comorbidities further complicate the clinical profile, reduce treatment compliance, and worsen prognosis, particularly in first-...

Obesity and depression - a bidirectional relationship and clinical implications

Background: Obesity has become a global civilization-related disease and constitutes an independent risk factor for numerous somatic disorders. Obesity can contribute to depression through low self-esteem, body image concerns, and stigmatization, while depression and chronic stress may promote obesity through emotional...

Anxiety and Depression in Pancreatitis: Mechanisms, Assessment, and Treatment.

The problem of comorbidity of non-psychotic mental and somatic disorders (a literature review)

The comorbidity of non‑psychotic mental and somatic disorders is viewed as a stable network of bidirectional relationships between affective, anxiety, personality, and behavioral psychopathology, on the one hand, and cardiometabolic, cardiovascular, pain, gastroenterological, and other somatic conditions, on the other....