Polypharmacy, commonly defined as the concurrent use of multiple medications, has emerged as a significant global health concern, especially among elderly patients with multimorbidity. It is associated with an increased risk of adverse drug reactions, drug–drug interactions, prolonged hospital stays, and poor medicatio...
Diya Agarwal, K. Reddy, G. Prasanna et al.· International Journal of Bas...· 0 citations
Background: Antibiotics are among the most commonly prescribed drugs in clinical practice and are frequently co-prescribed with other medications various indications. This polypharmacy increases the risk of drug-drug interactions, which can lead to adverse drug events, treatment failure and increased healthcare costs....
V. DrGanaviM, Jayashree V. Nagaral, P. DrDeepak et al.· 0 citations
Background: Older adults with psychiatric illness often take long-term antipsychotics along with medicines for chronic diseases, increasing the risk of potential drug–drug interactions (pDDIs) and adverse drug reactions (ADRs). Indian outpatient data are limited. The main objective of this study was to describe pDDIs i...
S. Mahato, T. Y. Sree Sudha, Kusum Kumari et al.· Nigerian Medical Journal· 0 citations
This narrative review aims to synthesize existing evidence on toxicity and overdose associated with commonly used palliative medications, with particular emphasis on opioids, paracetamol, tricyclic antidepressants, and psychotropic drugs, with particular emphasis on opioids.
Savan Kukadia· Asian Journal of Oncology· 0 citations
While modern therapies offer better safety profiles, specific combinations like valproate-lamotrigine or SSRI-tramadol require rigorous monitoring and Pharmacists must prioritize screening for enzyme-inducing AEDs to prevent therapeutic failure or toxicity in neuropsychiatric care.
Erwin Samsul, Sandrina Nur Yulianda, Rahmawati Eka Sari et al.· Journal of Pharmaceuticals a...· 0 citations
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