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Neural basis of compositional control

Assia Chericoni Justin M. Fine Taha S. Ismail Gabriela Delgado Salazar Melissa C. Franch Elizabeth Mickiewicz Ana G. Chavez Eleonora Bartoli D. Paulo Vaishnav Krishnan Mohamed Hegazy Alica M. Goldman Lu Lin G. Banks N. Giridharan M. Hasen N. Provenza A. Watrous Seng Bum Michael Yoo S. Sheth Benjamin Y. Hayden
Aug 2026 · Nature · Vol 658, pp. 163 - 173 · 2 citations · 78 references
Medicine

TL;DR

Behaviour of human participants in a prey-pursuit task reflects dynamic blending of goal-specific control policies, with hippocampus estimating latent states, anterior cingulate cortex orchestrating policy switches and orbitofrontal cortex supplying value-based contextualization rather than driving continuous policy updating.

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