Association of urinary albumin-to-creatinine ratio with all-cause and cardiovascular disease mortality risk in patients with osteoarthritis: a prospective cohort study
Aug 2026· Clinical Rheumatology· Vol 45, pp. 5829 - 5839· 0 citations· 27 references
Medicine
TL;DR
Elevated UACR is independently and incrementally associated with higher all-cause and CVD mortality in OA patients, especially in women and those with comorbid lung disease, and may function as an uncomplicated, non-invasive tool for predicting risk in OA.
Low-grade albuminuria may serve as an early biomarker of cardiovascular risk in otherwise healthy individuals, particularly in subgroups susceptible to hormonal or metabolic changes, and may be a practical tool for early risk stratification and prevention of CVD.
Minjeong Ko, Y. Jeong, J. Kim et al.· Yonsei medical journal· 0 citations
Abstract Central adiposity is a key driver of cardiovascular risk in chronic kidney disease (CKD), yet conventional obesity indices incompletely capture this risk. The weight-adjusted waist index (WWI) is an emerging anthropometric measure that integrates abdominal adiposity independent of body weight, but its prognost...
The findings should be interpreted as hypothesis-generating and suggest that adults without diabetes but with clustered metabolic abnormalities may warrant further longitudinal evaluation for kidney risk stratification.
Xiao-Han Xu, Shan-Hu Qiu, Xiao-Ying Zhou et al.· Journal of Endocrinological...· 0 citations
Highlights • Elevated GLR is independently associated with higher all-cause and CVD mortality in a J-shaped manner.• GLR showed comparable or modestly better discrimination than individual inflammatory biomarkers.• The association persisted across sensitivity, competing-risk, and subgroup analyses after multiple-testin...
UHR and UAR are independently associated with advanced CKM syndrome and have complementary clinical utility, and UAR may be preferred for early screening, whereas UHR may be better suited for CKM diagnosis and metabolic risk stratification.
Yi Deng, Miao Hu, Tian-Ran Ren et al.· Frontiers in Endocrinology· 0 citations
Cardiovascular-kidney-metabolic (CKM) syndrome integrates metabolic abnormalities, chronic kidney disease, and cardiovascular disease (CVD), with stages 0–3 representing a critical window for primary prevention. Whether the Chinese visceral adiposity index (CVAI) adds predictive value for CVD in this population r...
Long Feng, Geng Yang, He-Song Zeng et al.· Cardiovascular Diabetology· 0 citations
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