The Triglyceride‐Glucose (TyG) Index and Incident Diabetes and Cardiovascular Events in People Living With HIV‐1 Infection. A 14‐Year Observational Cohort Study
Sep 2026· European Journal of Clinical Investigation· Vol 56· 0 citations· 21 references
Medicine
TL;DR
The triglyceride‐glucose (TyG) index has shown predictive value for Type 2 diabetes mellitus (T2DM) and cardiovascular events (CVEs) in the general population, but its utility in PWH remains unclear.
Abstract
People living with HIV (PWH) are at increased risk for metabolic and cardiovascular diseases. However, there is no structured prevention strategy for these subjects. The triglyceride‐glucose (TyG) index has shown predictive value for Type 2 diabetes mellitus (T2DM) and cardiovascular events (CVEs) in the general population, but its utility in PWH remains unclear.
The atherogenic index of plasma (AIP) is a lipid‐based indicator of cardiometabolic risk. We examined whether AIP is associated with prevalent type 2 diabetes mellitus (T2DM) and fasting blood sugar (FBS) in patients with premature coronary artery disease (PCAD) and explored whether this association differed across Ira...
Raza Amani-Beni, G. Dabaghi, N. Mohammadifard et al.· Endocrinology, Diabetes & Me...· 0 citations
Lipotoxicity mediated by circulating free fatty acids is crucial in the pathogenesis of diabetes‐related sarcopenia, but the independent association and dose–response pattern between serum FFA levels and sarcopenia risk in T2DM patients remain poorly clarified.
Qian Yu, Min Ding, Hong-Yan Yu et al.· Geriatrics & Gerontology Int...· 0 citations
Background
The C-reactive protein-triglyceride glucose index (CTI) has recently been introduced as a novel composite biomarker that integrates inflammation and insulin resistance. However, the association between CTI and incident cardiovascular disease (CVD) in individuals with hypertension remains unclear.
Methods
W...
Yin Wang, Jie Luo, Zhao-Fu Tan et al.· Endocrinology and Metabolism· 0 citations
Depression and long‐term HbA1c variability are associated with adverse outcomes in type‐2 diabetes (T2D), which may be related to suboptimal self‐management practices and health‐related quality of life (HRQoL).
K. Wong, E. W. Chow, E. Lau et al.· Diabetes/Metabolism Research...· 0 citations
Advanced imaging research may improve major cardiovascular risk prediction in people ageing with HIV, as CACS better predicted adverse outcomes than Q-risk scores.
Maithili Varadarajan, Ruth Byrne, Abethale Al-Hussaini et al.· AIDS (London)· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.