Abstract Background Schizophrenia is associated with widespread abnormalities in large-scale brain organization; however, the mechanisms linking altered cortical hierarchy to disrupted neural communication and clinical symptoms remain unclear. By integrating functional connectivity gradient analysis and stepwise functi...
S. Joo, Jungsun Lee· Psychological Medicine· 0 citations
BACKGROUND
Schizophrenia is characterized by disruptions in large-scale brain networks, yet the specific relationship between visual-network connectivity and perceptual deficits such as impaired stereopsis remains unclear. We hypothesized that patients with schizophrenia would exhibit poorer stereoscopic acuity and alt...
Yong-Ming Wang, Zhen-Hua Zhu, Yu-Shan Xie et al.· Progress in Neuro-psychophar...· 0 citations
BACKGROUND
Understanding how disease-related connectome alterations relate to underlying molecular systems remains a major challenge in psychiatric disorders.
METHODS
Here we introduce BrainNetAnno (https://brainnetanno.readthedocs.io/en/latest), an open-source framework for molecular annotation of brain network conn...
Background and Hypothesis Negative symptoms in schizophrenia spectrum disorder (SSD) are associated with poor functional outcomes and reduced quality of life; however, effective treatments remain limited. A better understanding of the underlying brain mechanisms is needed to develop better treatments. Neuroimaging stud...
Keiko Kunitoki, B. Adhikari, A. Ankeeta et al.· bioRxiv· 0 citations
BACKGROUND
Schizophrenia is increasingly conceptualized as a disorder of circuit-level dysfunction. However, how thalamocortical abnormalities differ across cohorts with varying illness durations and relate to large-scale cortical hierarchical organization remains unclear.
METHODS
We analyzed resting-state functional...
Huan Huang, LENA PALANIYAPPAN, He-Chun Li et al.· Biological Psychiatry· 0 citations
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