Sep 2026· JOURNAL OF BIOLOGY AND GENETIC RESEARCH· 0 citations
TL;DR
It is concluded that P. falciparum remains the sole species in Sokoto State and recommends integrating molecular tools into malaria control programs to improve diagnostic accuracy.
Abstract
Abstract
This study examined the epidemiology, risk factors, and molecular confirmation of malaria
infection in selected households across Yabo, Gwadabawa, and Sokoto South Local Government
Areas (LGAs) of Sokoto State, Nigeria. A total of 660 participants were recruited, and data were
collected through structured questionnaires and blood analyses using microscopy, Rapid
Diagnostic Tests (RDTs), and Polymerase Chain Reaction (PCR). Microscopy identified
Plasmodium infection in 39.1% of individuals, while RDTs detected 38.9%. PCR confirmed all
Plasmodium falciparum cases and revealed submicroscopic infections undetected by conventional
methods. Malaria prevalence was significantly associated with occupation and blood group (p <
0.05). RDT sensitivity and specificity were 70% and 97%, respectively, relative to microscopy. The
study concludes that P. falciparum remains the sole species in Sokoto State and recommends
integrating molecular tools into malaria control programs to improve diagnostic accuracy.
To drastically reduce malaria prevalence in Nnewi communities, government intervention through mass chemotherapy and integrated vector control is recommended for the study area.
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OBJECTIVE
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STUDY DESIGN
An analytical cross-sectional study. Place and Duratio...
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