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Sep 2026

Statistical Theory of Lipid Membrane Conductivity and Stability Regulated by Membrane-Deforming Inclusions and External Fields

The formation of pores in bilayer lipid membranes is a key process in many biomedical and biotechnological applications. Pores are usually formed as a result of external influences, such as an electric field, lateral tension, or amphipathic peptides. The average characteristics of the pore formation process are deter...

O. V. Kondrashov, S. Akimov · 0 citations
Open access Aug 2026

Electroporation memory and cumulative transport in yeast cells: Refining the asymptotic model for multi-pulse protocols.

A continuous pore formation model adapted for the 8-pulse ESOPE protocol is proposed that provides a quantitative framework for optimising electrochemotherapy parameters in small-cell systems by accounting for cumulative transport and cellular scale variability.

Jéssica Rodrigues, R. Guedert, J. Anselmo et al. · 0 citations
Open access Sep 2026

Unraveling the dielectric heterogeneity response of cell lines under electroporation: a microfluidic single-cell on-chip system

In the clinical application of irreversible electroporation for tumor therapy, individual differences in cellular electrical responses often lead to the reliance on empirically selected treatment parameters, which easily cause over/under-treatment in patients and hinder the development of precision tumor therapy. To cl...

Li-Sheng Zhao, Yi-Ran Shu, Yan-Cheng Wang et al. · 0 citations
Sep 2026

Non-monotonic response of cell membrane permeabilization under nanosecond pulsed electric field from 1 Hz to 2 MHz: A numerical and experimental study

It is generally regarded that cell membrane permeabilization increases monotonically with the repetition rate of nanosecond pulsed electric field (nsPEF). However, our experiments showed that this was not always the case. In the high-conductivity culture medium (1 S/m), cell permeabilization showed increase (1–100 Hz),...

Fei-Yu Wu, Shu-Peng Wang, Kai Chen et al. · 0 citations
Dec 2026

Influence of Gradient Porosity Porous Transport Layer on Heat and Mass Transport Behavior of Proton Exchange Membrane Water Electrolyzer

A three-dimensional, nonisothermal electrochemical model, incorporating reconstructed pore structures, was developed to quantify how porous transport layer (PTL) microstructures regulate heat and mass transport in proton exchange membrane water electrolyzers (PEMWEs). Parametric simulations were conducted to evalua...

Kun Li, Xiao Chen, Yuan-Ming Li et al. · 0 citations
Sep 2026

Simplified formation of ultrasmall lipid bilayer between parallel micrometer channels using Laplace pressure for assessing membrane instability under shear flow

Microfluidic devices containing artificial cellular membranes have been developed for biology, biosensors, and bioengineering. Although forming a lipid bilayer between two microchannels has advantages for integrating cellular membrane functions into continuous chemical processing and evaluating cellular membrane respon...

Naoyuki Takezoe, Itsuo Hanasaki, Rikiya Watanabe et al. · 0 citations

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