Clade-specific evolution and genome plasticity underlying antimicrobial resistance in Enterococcus faecium

Journal of Global Antimicrobial Resistance

Genetic architecture and functional dynamics of integrons in Staphylococcus aureus resistance

Understanding integron dynamics in S. aureus is crucial for informing antimicrobial stewardship, infection control strategies, and future interventions aimed at limiting the spread of MDR pathogens.

Simulating the host niche: balancing complexity and control in the experimental evolution of antibiotic resistance and pathoadaptation

Abstract The ‘ESKAPE’ pathogens cause the majority of antibiotic-resistant infections in humans, with associated mortality expected to surpass that of cancer by 2050. Outbreak strains of these pathogens often demonstrate a remarkable ability to establish infection and easily acquire novel antimicrobial resistance mecha...

Genomic characterisation of vancomycin-resistant Enterococcus faecium with Tn1546-plasmid rep17 in obstetrics and gynaecology settings in Algeria

Genomic attributes of two clinical VREfm ST80 isolates are reported, harbouring a vanA-carrying rep17 plasmid in Algeria highlighting the presence of the epidemic VREfm ST80 clone evolving in healthcare settings.

Twenty-Five Years of Escherichia coli Antimicrobial Resistance in Bangladesh: A One Health Review of Phylogeny and Trends

This review is the first to integrate 25-year temporal trends, phylogenetic diversity, and One Health transmission dynamics of E. coli antimicrobial resistance in Bangladesh from 2000 to 2025.

Pan-genome analysis reveals the triangle mechanisms of antibiotic resistance, pathogenicity, and biofilm formation in Enterococcus faecalis

Critical insights into the development of multidrug resistance in nosocomial pathogens are provided and could enlighten novel drug designs and strategies to combat infections in both clinical and environmental settings.