Applications and prospects of the immunomodulatory and regenerative capabilities of gingival mesenchymal stem cells for chronic inflammation treatment

Applications of Mesenchymal Stromal Cells for Treatment of Diseases

This review provides a comprehensive framework for developing safer, standardized, and clinically transformative therapies based on MSCs, and explores emerging strategies to enhance the activity of MSCs, including pretreatment and activation, lifestyle intervention, and genetic engineering techniques.

Light-Based Therapies for Metabolic Modulation of Mesenchymal Stem Cells in Regenerative Dentistry

Periodontal diseases and temporomandibular disorders are characterized by chronic inflammation and progressive destruction of supporting tissues, leading to functional and aesthetic impairments. In this context, regenerative dentistry has increasingly focused on minimally invasive strategies capable of restoring tissue...

Immunomodulatory Properties of Mesenchymal Stem Cells and Their Extracellular Vesicles: Potential Clinical Applications in Autoimmune Diseases

Mesenchymal stem cells (MSCs)/mesenchymal stromal cells and their extracellular vesicles (EVs), particularly exosomes, have emerged as therapeutic candidates in regenerative medicine due to their multipotency, low immunogenicity, and extensive immunomodulatory properties. This narrative review provides a narrative synt...

Innovative Bioengineering Strategies to Enhance Dental Stem Cell Therapeutic Effects in Oncology Treatments.

This review critically analyzes the immunoregulatory pathways involved in inflammatory and immune-related disorders, and directly links these mechanisms to the challenges within the tumor microenvironment.

[Research progress on the application of stem cells and their derivatives in chronic wound repair].

Advances and mechanisms in the application and treatment of functionalized stem cells and their derivatives in allergic rhinitis

Allergic rhinitis (AR) is characterized by Th2/Th17/Treg immune imbalance and nasal mucosal barrier damage, and current treatments struggle to restore immune homeostasis. Mesenchymal stem cells (MSCs) and their exosomes can exert anti-inflammatory and barrier-repairing effects through paracrine pathways, but natural MS...