With the escalating impacts of climate change, drought stress (DS) is significantly decreasing water accessibility and availability, causing substantial direct and indirect economic repercussions within agricultural systems. Addressing the needs of a growing global population necessitates urgent advancements in breeding DS-tolerant crops while maintaining high yields. This urgency demands a fast and adaptable defensive strategy to mitigate the adverse effects of DS on crop productivity. Accelerating such developments requires leveraging advanced omics-assisted breeding (e.g., genomics, transcriptomics, proteomics, and metabolomics), genetic engineering (e.g., transgenic technology, and genome editing), machine learning, precise phenotyping, crop wild relatives, and speed breeding. These fast-forward methods present highly promising avenues for the design of future crops that can withstand DS pressures. In summary, we propose an innovative approach termed the “OGS trio,” which encompasses omics integration, genetic engineering, and speed breeding. This trio stands composed to transform efforts against DS, offering significant potential for developing drought-tolerant crops to achieve and food security amidst climate change.
Drought constitutes one of the most pervasive abiotic constraints limiting global crop productivity, with its frequency and intensity projected to increase substantially under ongoing climate change. This narrative review synthesises contemporary evidence on the genetic, physiological, and agronomic dimensions of drought resilience in major food crops, drawing on peer-reviewed literature published primarily between 2000 and 2026. Physiologically, drought impairs stomatal conductance, suppresses photosynthetic carbon assimilation, disturbs osmotic equilibrium, and restricts root-mediated water acquisition, with reproductive stages being disproportionately vulnerable. At the genetic level, the deployment of quantitative trait loci (QTL) mapping, transcription-factor engineering, CRISPR-Cas9 genome editing, and the overexpression of stress-responsive functional genes has opened novel avenues for enhancing tolerance without compromising yield potential. Breeding programmes have increasingly integrated marker-assisted selection (MAS) and genomic selection to accelerate genetic gain, whilst high-throughput phenotyping platforms now enable rapid assessment of drought-adaptive traits at a population scale. Agronomic strategies, including deficit irrigation, conservation tillage, intercropping, and application of plant growth-promoting rhizobacteria (PGPR), provide complementary levers for sustaining productivity under water-limited conditions. Emerging integrative approaches that combine multi-omics, digital precision agriculture, and policy-enabled climate-smart frameworks are highlighted as critical pathways for translating laboratory and field insights into scalable solutions. The review identifies persistent knowledge gaps—including the limited translation of genomic advances to smallholder contexts and the underexplored potential of microbiome engineering—and calls for a convergence of disciplinary expertise, equitable technology transfer, and coherent policy support to achieve drought-resilient food systems globally.
B. Santhosh, V. Sanjivkumar, H. B. Gowda et al.· Journal of Advances in Biolo...· 0 citations
Sustainable crop development aims to maintain or increase yields while reducing environmental impact and managing the challenges imposed by climate change. As the global population grows and arable land becomes scarcer, the integration of molecular breeding with bioinformatics has emerged as an effective strategy for long-term crop improvement. Bioinformatics enables researchers to analyze and interpret the vast quantities of genetic data generated by high-throughput sequencing, making it possible to identify molecular markers, candidate genes, and regulatory networks linked to specific agronomic traits, which breeders then translate into focused, ecologically sustainable breeding programs. This approach has enabled major progress across several fronts: the identification of genes conferring resistance to biotic stressors (pests, pathogens) and abiotic stressors (drought, salinity, heat); the development of nutrient-efficient, low-input crop varieties; the improvement of agronomic performance and nutritional quality through identification of yield- and quality-related genes; and the conservation and deployment of genetic diversity to safeguard long-term breeding sustainability. By combining genomic data with precision breeding techniques, researchers are developing crops that are better adapted to a growing population and a changing climate, positioning the integration of molecular breeding and bioinformatics as a central pillar of future global food security.
Muhammad Shahid Iqbal, Z. Sarfraz, Muhammad Mujahid et al.· Frontiers in Plant Science· 0 citations
Agricultural systems are increasingly challenged by climate change, resource scarcity, environmental degradation, and the need to ensure food security for a growing global population. Addressing these multifaceted challenges requires innovative, science-driven approaches that enhance productivity while promoting ecological sustainability. This editorial examines the evolving role of plant biotechnology as a key driver of modern agricultural advancement, highlighting recent developments in genomics, multi-omics technologies, molecular breeding, genome editing, plant tissue culture, and digital agriculture. It discusses how these technologies contribute to the development of resilient crop varieties with improved tolerance to biotic and abiotic stresses, enhanced nutrient-use efficiency, and superior agronomic performance. The editorial further emphasizes the integration of artificial intelligence, high-throughput phenotyping, bioinformatics, and systems biology into precision crop improvement, enabling more efficient translation of molecular discoveries into field applications. The importance of interdisciplinary collaboration, responsible innovation, biosafety, and science-based regulatory frameworks is also considered in supporting the sustainable deployment of emerging biotechnologies. Looking ahead, the convergence of advanced molecular tools with computational and ecological sciences is expected to accelerate the development of resilient agricultural systems capable of addressing future environmental and food production challenges. Continued investment in research, technological innovation, and international collaboration will be essential to maximize the societal and environmental benefits of next-generation crop improvement strategies.
Md. Mosharraf Hossen· Journal of Agriculture and F...· 0 citations
Plant breeding has progressed from phenotype-based selection to increasingly precise genetic and agronomic interventions. Advances in molecular breeding, genome engineering, and crop management have improved productivity, but have also promoted the widespread use of genetically uniform cultivars optimized for controlled production systems. While uniformity facilitates predictability and mechanization, it may constrain adaptive capacity under increasingly variable environmental conditions. In parallel, recent developments in digital agriculture, including high-resolution phenotyping, remote-sensing, molecular diagnostics, and AI-assisted decision support, are transforming the ability to monitor and manage biological variation across spatial and temporal scales. In this review, we examine how these technological advances intersect with emerging concepts in crop diversity and reproductive biology. We discuss how digital agriculture enables improved characterization of genotype-environment interactions and consider reproductive mechanisms that expand the accessible breeding space beyond conventional biparental crossing schemes, including haploid induction and multi-parental breeding. These approaches provide opportunities to accelerate trait introgression, generate novel genetic combinations, and overcome reproductive barriers. We argue that digital and diagnostic agriculture provide an informational framework for the deployment and evaluation of genetically heterogeneous plant populations. Together, recent advances suggest that technological precision and biological diversity can be integrated into breeding strategies that improve productivity and resilience.
Saurabh Joshi, Yanbo Mao, R. Gross-Hardt· Journal of Experimental Bota...· 0 citations
The review summarizes practical experiences in using mutation breeding for crop improvement in South-Eastern Europe (SEE) and Central Asia (CA), demonstrating that mutation breeding can be a field-validated, effective approach for developing climate-resilient crops. Drawing on coordinated research conducted within national breeding programs and international initiatives supported by FAO/IAEA, applied methodologies, trait-evaluation strategies, and concrete breeding outputs in cereals, legumes, and industrial crops are presented. The use of gamma irradiation, fast neutrons, and chemical mutagens has successfully generated stable mutant lines stable mutant lines with enhanced traits, such as increased thousand-grain weight in wheat, altered oil quality in sunflower, and improved drought tolerance in common bean and sesame. The integration of classical pedigree selection with modern breeding tools such as high-throughput phenotyping, molecular and biochemical markers, and doubled-haploid technology has enabled earlier and more efficient identification of superior genotypes in mutation breeding programs. The review underscores the practical relevance of mutation breeding in contemporary pipelines to maintain yield stability and quality under adverse environmental conditions.
Sandra Cvejić, Aleksandra Radanović, D. Trkulja et al.· Agronomy· 0 citations
Drought is recognized as the primary abiotic stress limiting global crop productivity and poses a significant threat to food security. Consequently, the genetic improvement of drought tolerance has become a priority for modern plant breeding. Developing resilient cultivars requires a fundamental understanding of the physiological, biochemical, and molecular mechanisms that plants employ to counteract water deficits. This review provides a comprehensive analysis of drought-induced effects across various developmental stages in legumes, detailing the signaling networks that facilitate stress perception and response. Furthermore, we evaluate the experimental parameters and methodologies frequently used to assess drought tolerance, weighing their respective advantages and limitations. Finally, we analyze the revolutionary role that high-throughput phenotyping could play in stress assessment and precision breeding.
Andrea Fernández-Gutiérrez, Alvaro F. Rodriguez-Torres, A. Encina et al.· Frontiers in Plant Science· 0 citations