This work evaluates pre-trained embeddings from four state-of-the-art open-source SFMs across three datasets in zero-shot and k-shot cross-lingual settings for multi-class PD severity assessment and shows that pre-trained speech embeddings enable meaningful cross-lingual transfer, although performance is sensitive to dataset properties, preprocessing, and adaptation strategy.
Abstract
Parkinson's disease (PD) often manifests through speech impairments, facilitating accessible, non-invasive, and cost-effective severity assessment for early diagnosis and progression tracking. Despite advances in speech foundation models (SFMs), their cross-lingual generalization for PD severity multi-class classification remains underexplored due to limited labeled data, a lack of explainable methods and variability across languages and datasets. In this work, we evaluate pre-trained embeddings from four state-of-the-art open-source SFMs across three datasets in zero-shot and k-shot cross-lingual settings for multi-class PD severity assessment. Our results show that pre-trained speech embeddings enable meaningful cross-lingual transfer, although performance is sensitive to dataset properties, preprocessing, and adaptation strategy. Misclassifications under these conditions related to inter-speaker variability and atypical speech patterns highlight the need for more robust feature extraction and modeling for PD severity assessment while emphasizing the importance of explainability for reliable clinical insights.
This work proposes a closed-form ridge residualization of S3M features against external VoxLingua107 language embeddings, fitted using only healthy-control speech, which consistently improves cross-lingual PD-detection performance while correcting the high-specificity/low-sensitivity failure.
Minu Kim, Eunjung Yeo, Kwanghee Choi et al.· 2 citations
Speech Large Language Models (Speech LLMs) have shown strong performance across diverse tasks, yet their utility for pathological speech analysis remains underexplored. In this work, we investigate the effectiveness of internal representations from encoder and decoder components of Speech LLMs for Parkinson's Disease (...
Sarthak Giri, Z. Pang, Tatsuya Kawahara· 0 citations
Background: Alzheimer's disease (AD) affects over 55 million people worldwide, and early detection through speech analysis offers a low-cost, non-invasive alternative to neuroimaging. However, clinical deployment of speech-based classifiers faces underexplored challenges: domain shifts across recording environments, li...
A. Singh· NSRI Student Research Journa...· 0 citations
The role of speech preprocessing and dataset curation across widely used benchmarks for speech-based AD detection is revisited, suggesting that ``cleaner''speech datasets are not necessarily more reliable for real-world AD detection.
Lu Sun, Shreeram Suresh Chandra, Lin Zhang et al.· 0 citations
Parkinson’s disease (PD) is a progressive neurodegenerative disorder that severely impairs motor control and quality of life. Conventional diagnostic approaches such as clinical motor assessment and neuroimaging are expensive, invasive, and lack sensitivity for early-stage detection. However, subtle alterations in voca...
This work highlights the need to audit feature transferability and report worst-case domain robustness in cognitive speech screening by proposing a fusion method that integrates XLM-R text baseline scores with evidence anchors selected during training.
Zi-Jian Lu, Si-Zhe Liu, Yin Zhang et al.· 0 citations
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