Skip to content

Cross-Lingual Parkinson's Disease Severity Assessment Using Pre-trained Speech Embeddings: A Multi-Class Evaluation

Sep 2026 · 0 citations · 44 references
Engineering Computer Science

TL;DR

This work evaluates pre-trained embeddings from four state-of-the-art open-source SFMs across three datasets in zero-shot and k-shot cross-lingual settings for multi-class PD severity assessment and shows that pre-trained speech embeddings enable meaningful cross-lingual transfer, although performance is sensitive to dataset properties, preprocessing, and adaptation strategy.

Abstract

Parkinson's disease (PD) often manifests through speech impairments, facilitating accessible, non-invasive, and cost-effective severity assessment for early diagnosis and progression tracking. Despite advances in speech foundation models (SFMs), their cross-lingual generalization for PD severity multi-class classification remains underexplored due to limited labeled data, a lack of explainable methods and variability across languages and datasets. In this work, we evaluate pre-trained embeddings from four state-of-the-art open-source SFMs across three datasets in zero-shot and k-shot cross-lingual settings for multi-class PD severity assessment. Our results show that pre-trained speech embeddings enable meaningful cross-lingual transfer, although performance is sensitive to dataset properties, preprocessing, and adaptation strategy. Misclassifications under these conditions related to inter-speaker variability and atypical speech patterns highlight the need for more robust feature extraction and modeling for PD severity assessment while emphasizing the importance of explainability for reliable clinical insights.

View source

Similar papers

Preprint Sep 2026

Language Orthogonalization of Self-Supervised Speech Representations for Cross-lingual Parkinson's Detection

This work proposes a closed-form ridge residualization of S3M features against external VoxLingua107 language embeddings, fitted using only healthy-control speech, which consistently improves cross-lingual PD-detection performance while correcting the high-specificity/low-sensitivity failure.

Minu Kim, Eunjung Yeo, Kwanghee Choi et al. · 2 citations
Preprint Sep 2026

Exploiting Speech LLM Representations for Multilingual and Cross-Lingual Parkinson's Disease Detection

Speech Large Language Models (Speech LLMs) have shown strong performance across diverse tasks, yet their utility for pathological speech analysis remains underexplored. In this work, we investigate the effectiveness of internal representations from encoder and decoder components of Speech LLMs for Parkinson's Disease (...

Sarthak Giri, Z. Pang, Tatsuya Kawahara · 0 citations
Open access Aug 2026

Speech-Based Alzheimer's Detection Under Controlled Acoustic Perturbations: A Baseline Study of Class Imbalance and Robustness

Background: Alzheimer's disease (AD) affects over 55 million people worldwide, and early detection through speech analysis offers a low-cost, non-invasive alternative to neuroimaging. However, clinical deployment of speech-based classifiers faces underexplored challenges: domain shifts across recording environments, li...

A. Singh · 0 citations
#artificial intelligence Preprint Aug 2026

Cleaner Speech, Weaker Generalization: Revisiting Pitt-Derived Benchmarks for Alzheimer's Disease Detection

The role of speech preprocessing and dataset curation across widely used benchmarks for speech-based AD detection is revisited, suggesting that ``cleaner''speech datasets are not necessarily more reliable for real-world AD detection.

Lu Sun, Shreeram Suresh Chandra, Lin Zhang et al. · 0 citations
Open access Aug 2026

Large Language and Ensemble Powered Enhanced Parkinson's Detection Model

Parkinson’s disease (PD) is a progressive neurodegenerative disorder that severely impairs motor control and quality of life. Conventional diagnostic approaches such as clinical motor assessment and neuroimaging are expensive, invasive, and lack sensitivity for early-stage detection. However, subtle alterations in voca...

Seema Gaba, Harpreet Kaur, Arun Singh · 0 citations
#natural language process... Preprint Sep 2026

Why Alzheimer's Speech Screening Fails to Generalize: Bridging the Deployment Gap via Cross-Corpus Evidence Anchoring

This work highlights the need to audit feature transferability and report worst-case domain robustness in cognitive speech screening by proposing a fusion method that integrates XLM-R text baseline scores with evidence anchors selected during training.

Zi-Jian Lu, Si-Zhe Liu, Yin Zhang et al. · 0 citations

Related blog posts

MIT News · Artificial Intelligence Oct 15, 2026

AI model decodes the language cells use to communicate

A new computational approach reveals how cells communicate to assemble into tissues. This could accelerate stem cell engineering, improve disease models, and inform therapies.

Microsoft Research Blog Oct 15, 2026

Proof-based general-purpose computing with Magnetar

Zero-knowledge proofs can verify computing results without rerunning workloads or exposing sensitive data. Magnetar helps bring them into the mainstream with support for standard programming languages, major speed gains, and quantum-resistant security. The post Proof-based general-purpose computing with Magnetar appeared first on Microsoft Research.

MIT News · Artificial Intelligence Sep 24, 2026

Estimating suicide risk from text

A new language-processing tool could help identify the highest-risk individuals from natural language, enabling swifter interventions.

We use cookies to run the site and, with your consent, for analytics and to show ads. See our Cookie Policy.