Evaluating the protective potential of Aspilia africana against phenanthrene-induced cardiorenal injury: biochemical and computational approaches

Asiatic Acid Ameliorates Chlorpyrifos-Induced Toxicity in Rats: Biochemical and Histopathological Insights

This study provides the first demonstration that asiatic acid exerts robust systemic antioxidative, hepatoprotective, and neuroprotective effects against CPF-induced toxicity, highlighting AA’s therapeutic potential for mitigating organophosphate pesticide poisoning.

Hepatoprotective effects of cinnamic acid against carbon tetrachloride–induced liver injury in a mouse model

Cinnamic acid may exert hepatoprotective effects against CCl₄-induced liver injury, with secondary favorable effects on renal biochemical markers of CCl₄-induced systemic toxicity, by modulating oxidative and inflammatory pathways.

Pulicaria odora as a Natural Antioxidant Remedy for Metribuzin-induced Toxicity

Co-administration of P. odora extract significantly reversed metribuzin-induced toxicity in Wistar rats, restoring biomarkers and alleviating hepatic and renal toxicity by reducing transaminases, urea, creatinine, cholesterol and triglycerides and its antioxidant properties were highlighted.

The Therapeutic Potential of Pelargonidin against Perflourooctane Sulfonate Instigated Cardiac Toxicity via Modulating Nrf-2/Keap-1 Pathway, Inflammatory, Apoptotic and Histological Profile

Investigating the hepatoprotective effects of Lonicera confusa against acetaminophen-induced acute liver injury: a systematic pharmacological approach.

Results suggest SYH mitigates ALI by inhibiting the pro-inflammatory TLR4/MYD88/NF-κB pathway and activating the antioxidant Keap-1/Nrf2/HO-1/NQO1 pathway.

Protective effects of sanggenon C against acetaminophen-induced hepatotoxicity via modulation of oxidative stress and inflammation

It is suggested that sanggenon C mitigates acetaminophen-induced hepatotoxicity by regulating oxidative stress and inflammatory pathways and may have potential as a natural hepatoprotective agent.